Sometimes Studio comes up with an error message informing the user that a temporary file is missing, preventing the saving a file, be it automatically in the background or manually by the user.
For me most often the file name is SDLTempFileRegen but sometimes it's something like tmp... Search for missing tmp file / SDLTempFileRegen in the Community and you'll find several posts concerning this.
I found that the error can be overcome if I create a file with the same name in the same path as in the error message.
Hence, I would propose that Studio should recreate the missing file itself (or remove the dependency on that file) and only alert the user if it still can't save the file