Problems after updating Trados 2021 to SR1 - 16.1.5.4270

Today, after updating:

- pre-translation not possible (errors). I tried with two very diferent files. A very old file and a new file.

- after translating a sentence, after hiting ctrl+enter, cursor goes to next segment but Trados copies source to target. 

Any help?

Should I uninstall Trados completly and install it again? If yes, what should I do with my TM and termbase?

Thank you for any help.