"Save Target As" greyed out in Trados 2017

I haven't been able to use "Save Target As" since I upgraded to Trados 2017, since it is greyed out. When would this occur? What should I try?

I do have a file open for translation.

My first project with Trados 2017 was a Single Document (which I ended up submitting after pasting the translation manually).
I uninstalled and re-installed (and installed the current update), and am trying again with a second project.
I started it through New Project though it is also a single document.

I am a Translator,
and my languages are Japanese to English.

I have used Trados 2013 and 2015 before, and don't remember having such a problem.

Both of the source files (one for each project) have been Excel.

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